Add Keating Memorial Research: Measuring the Effect of Low-carb Ingredients on Blood Sugar

Keating Memorial Research%3A Measuring the Effect of Low-carb Ingredients on Blood Sugar.-.md

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+<br>This self-experiment is being done as part of the Keating Memorial Self-Research Project. A couple of other people from the Open Humans community are also running the same experiments. If you’re interested in joining in, let me know in the comments or send me a PM. Calibrate continuous [GlycoMode blood glucose support](http://britta-merzenich.de/index.php?title=Revolutionizing_Glycobiology:_The_Emergence_Of_Glyco_Mode) glucose meter: started 2/18, report tbd. Note: If you want to see the full post with links, you can do so here. I had posted this experimental plan on r/QuantifiedSelf on Reddit and was pointed here. The Keating Memorial Self-Research Project seems like both a great way to honor an important innovator and for the QS community to support each other in their research. I know the project logs were supposed to be started last week, but hopefully it’s still ok for me to add my project and get feedback. The background and proposed experiment is below. I’d love to get feedback on my experimental design before I start.<br>
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+<br>If you’re interested, please take a look and leave your feedback/critique in the comments. I’ve got Type 2 diabetes and have recently gotten involved in more rigorous self-tracking and self-experimentation. For my next set of experiments, I want to measure the effect of different foods on blood sugar. When I tried this before, I added ingredients to my normal meals measured the change in my normal BG trends (see Next Experiments). This proved too noisy and I couldn’t get a clean measure of the effect of even pure glucose in a reasonable number of measurements (see Next Experiments). This time, I have a continuous glucose monitor (Freestyle Libre, post coming soon on accuracy vs. Determine effect of combining ingredients on same. 1. Calibrate Instruments: Over several days, measure blood sugar by both CGM (Freestyle Libre) and BGM (Freestyle Lite). 2. Establish Baseline: Monitor blood sugar while skipping breakfast & lunch (both food & insulin) to identify a period of time where my [blood sugar](https://www.foxnews.com/search-results/search?q=blood%20sugar) is stable for  [GlycoMode Review](https://www.fuzhuangwang.com/home.php?mod=space&uid=615914&do=profile) a long enough (need at least 2-4 hours).<br>
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+<br>Based on previous experiments, I’ll need to wait until after lunch. To reduce potential noise, need to be careful not to overeat or eat late the night before. 3. Measure Food Effects: For each ingredient or combination of interest, follow the same procedure as in the baseline, but at the selected time, consume a fixed, measured quantity of the ingredient and monitor blood sugar by CGM and BGM (every 30 min.) for 2 hours or until my blood sugar is stable for at least 1 h. Based on the initial results, I will test different quantities of the ingredients until I have a [dose-response curve](https://www.change.org/search?q=dose-response%20curve) with BG increases from 0 to 40 mg/dL or the quantity exceeds what I would reasonably consume in a sitting, whichever is smaller. Number experiments will be at least 3 per ingredient or combination. Current design tests one ingredient at a time. This is a lot simpler and lets me get results for the first ingredients sooner, but does introduce a systematic variation between ingredients (the week). My thought was to mitigate this by re-testing [GlycoMode glucose support](https://rikkiepedia.nl/index.php?title=GlycoMode:_Revolutionizing_Glycobiology_Research) at some frequency to measure week-to-week variation. Do you think this is sufficient or is there a better design? I’m not planning to repeat quantities of a given ingredient multiple times, but instead vary the quantity. Since the end result of interest is change in BG as a function of quantity, I figured this would be more experimentally efficient. Are there any problems with this approach? Since experiments will be done on M, W, F, there will be a 1-2 day washout period between ingredients. Is this sufficient or do I need to separate ingredients by week to ensure a two day washout? Are there any other ingredients I shouls test? Is anyone interested in joining the experiment?<br>
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